Health Conditions - For Everyone

Causes of Depression
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Causes of depression

The cause of depression is not known. It is thought to be due to a combination of a number of factors:


The neurotransmitters in the brain control mood, thinking, sleep, appetite and behaviour and if these neurotransmitters become unbalanced, depression can be the result. The main neurotransmitters affected are: serotonin, dopamine, GABA, but there are many others which play a part in the brain's function.


The most common reason for depression is experiencing a stressful life event, such as the loss of a loved one, divorce, break-up, losing a job, trauma. Even positive events can cause depression, if they are significant enough - getting married, buying a home for the first time, having a baby, promotion or getting a huge pay rise.



Researchers have determined that some types of depression tends to run in families, which suggests that in these people, there is a genetic link which has been a factor in causing the depression, but this genetic link is not the sole factor.

Research into the genetic cause of depression suggests that people who have certain genes that are a risk factor for depression will develop it, if there are environmental or other factors which trigger the genes to cause depression to start.


Some people seem to have a more negative or pessimistic view on life, so when stressful events occur, this may trigger depression, from a mild case, to a more severe one.


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  Last reviewed: 24 January 2009 || Last updated: 21 March 2009


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NOTE: Mega doses of any type of vitamin, mineral, amino acid or herbal supplement cannot cure illnesses and in fact can be very dangerous and produce toxic side effects and interfere with medicine you are taking. Always ensure you consult your doctor before taking any type of complementary supplements.
Disclaimer: This guide is not intended to be used for diagnostic or prescriptive purposes. For any treatment or diagnosis of illness, please see your doctor.


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