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Threonine

Facts

Why threonine is good for you

Threonine is an essential amino acid that helps to maintain the proper balance of protein in the body.

It is important for the formation of collagen and elastin in the skin, and aids to fight fatty liver, when combined with aspartic acid and methionine.

Important threonine facts

  • Threonine is present in high concentrations in the heart, the central nervous system, and skeletal muscle
  • It enhances the immune system by aiding in the production of antibodies and promotes thymus growth and activity – newborns have high amounts of threonine which decreases with age
  • Threonine requirements increase if high levels of stress or trauma are experienced
  • Other nutrients are better absorbed when threonine is also present

Threonine works best with

Health

Threonine and health

  • Depression – threonine has been used to successfully treat mild depression in some studies.

Talk to a medical professional about threonine supplements before taking them

Deficiency

Groups at risk of threonine deficiency

Deficiency is rare, but can occur in the following individuals:

  • People on low protein diets – people who are not eating enough protein foods may not get enough threonine in their diet
  • Vegans and vegetarians – people who are on a strict vegetarian diet may suffer from a threonine deficiency if their diet is deficient in protein

People in these groups at risk of threonine deficiency should talk to a medical professional about threonine supplementation before taking it.

Symptoms of threonine deficiency

Deficiency may result in irritability and a generally difficult personality, including severe and sudden mood changes.

As threonine is a precursor of isoleucine, imbalance may result if the synthesis rate from aspartate is incorrect.

Food sources

Threonine in food

FOOD AMOUNT
Threonine
(mg)
Bacon, pan-fried
28g
4200
Tuna, canned in oil
1 can (171g)
2184
Snapper, cooked
1 fillet (170g)
1960
Halibut, cooked
1/2 fillet (159g)
1860
Chicken breast meat only, roasted
1 cup (140g)
1834
King mackerel, cooked
1/2 fillet (154g)
1756
Soybeans, dry roasted
100g
1719
Lean veal leg, cooked
100g
1604
Lean veal sirloin, cooked
100g
1483
Lean shoulder lamb, cooked
100g
1460
Lean round beef, cooked
100g
1443
Lean pork loin chops, cooked
100g
1422
Lean veal shank, cooked
100g
1407
Pink salmon, cooked
1/2 fillet (124g)
1390
Turkey breast meat only, roasted
100g
1337
Yellow fin tuna, cooked
100g
1314
Blue fin tuna, cooked
100g
1311
Alaskan king crab, cooked
1 leg (172g)
1275

 

Daily intake

Threonine recommended daily intake (RDI)

RDA 68mg/kg body weight (infants)
28mg/kg body weight (children)
8-10mg/kg body weight (adults)
TOLERABLE UPPER LIMIT 150-500mg
TOXIC LEVELS No information available

 

Toxicity

Overdosage, toxicity and cautions for threonine

No information available.

Precautions

Precautions

 

Interactions

Interactions

 

References

References

  • Osiecki H, Meeke F, Smith J, The Encyclopaedia of Clinical Nutrition – Volume 1: The Nervous System, BioConceps Publishing QLD 2004

Last reviewed and updated: 8 May 2024

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