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Valine

Facts

Why valine is good for you

Valine is an essential amino acid and is required for muscle metabolism, repair and growth of tissue and maintaining the nitrogen balance in the body. Valine also assists to regulate blood sugar and energy levels.

Important valine facts

  • Valine is part of the three branched chain amino acids (BCAA) – the other two are leucine and isoleucine

Valine works best with

Health

Valine and health

  • Drug addiction – valine is good for correcting the type of severe amino acid deficiencies that can be caused by drug addiction.

Talk to a medical professional about valine supplements before taking them

Deficiency

Groups at risk of valine deficiency

Deficiency is rare, but can occur in the following individuals:

  • People on low protein diets – people who are not eating enough protein foods may not get enough valine in their diet
  • Vegans and vegetarians – people who are on a strict vegetarian diet may suffer from a valine deficiency if their diet is deficient in protein
  • Drug addicts – may be deficient in all nutrients

People in these groups at risk of valine deficiency should talk to a medical professional about valine supplementation before taking it.

Symptoms of valine deficiency

A deficiency of valine may affect the myelin covering of the nerves.

Another effect of valine deficiency is Maple Syrup Urine Disease (MSUD). MSUD is caused by the inability to metabolise leucineisoleucine, and valine. The disease is named because people with this disease have urine that smells like maple syrup.

Food sources

Valine in food

FOOD AMOUNT
Valine
(mg)
Tuna, canned in oil
1 can (171g)
2567
Snapper, cooked
1 fillet (170g)
2303
Gruyere cheese
100g
2243
Halibut, cooked
1/2 fillet (159g)
2186
Romano cheese
100g
2183
Chicken breast meat, roasted
1 cup (140g)
2155
Swiss cheese
100g
2139
Goat cheese, hard
100g
2100
King mackerel, cooked
1/2 fillet (154g)
2064
Lean veal leg
100g
2029
Soybeans, dry roasted
100g
1976
Lean veal sirloin, cooked
100g
1877
Lean shoulder lamb, cooked
100g
1842
Edam cheese
100g
1810
Lean round beef, cooked
100g
1792
Lean veal shank, cooked
100g
1778
Lean pork loin chops, cooked
100g
1689
Turkey leg meat, roasted
1 cup
1550

 

Daily intake

Valine recommended daily intake (RDI)

RDA 92mg/kg body weight (infants)
25mg/kg body weight (children)
14mg/kg body weight (adults)
TOLERABLE UPPER LIMIT 500-1000mg
TOXIC LEVELS No information available

 

Toxicity

Overdosage, toxicity and cautions for valine

Very high levels of valine can cause symptoms such as:

  • a crawling sensation on the skin
  • hallucinations.

Precautions

Precautions

People with kidney or liver disease should be careful in consuming high intakes of amino acids without consulting their doctor.

Interactions

Interactions

 

References

References

  • Osiecki H, Meeke F, Smith J, The Encyclopaedia of Clinical Nutrition – Volume 1: The Nervous System, BioConceps Publishing QLD 2004

Last reviewed and updated: 8 May 2024

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