Monday, November 24, 2025

Glycine

Why glycine is good for you

Glycine is a sweet-tasting, non-essential amino acid that can be produced from serine and threonine, so dietary intake is not essential.

Glycine is required to build protein in the body. It is required for the synthesis of nucleic acids, the construction of RNA as well as DNA and synthesis of bile acids and other amino acids in the body.

Glycine is also found to be useful in assisting with the absorption of calcium in the body. It helps in retarding degeneration of muscles as it helps to supply extra creatine in the body. Glycine is important in the body’s manufacture of hormones responsible for a strong immune system.

Important glycine facts

  • Glycine is used by the nervous system and functions as an inhibitory neurotransmitter, which makes it important to help prevent epileptic seizures
  • Glycine is also used in the treatment of manic depression and hyperactivity
  • Glycine is found in all cells of the body, but it is found in large amounts in the prostate fluid and may be important in prostate health
  • Glycine also participates in the major energy producing biochemical processes in the body

Groups at risk of glycine deficiency

None reported.

Symptoms of glycine deficiency

Few people are glycine deficient, partly because the body makes its own supply of it and partly because it is abundant in many different food sources.

Glycine and health

  • Repairing damaged tissue – high concentrations of glycine are found in the skin and connective tissues, which aids in repair of damaged tissue

Talk to a medical professional about glycine supplements before taking them

Glycine in food

FOODAMOUNT
Glycine
(mg)
Lean veal sirloin, cooked
100g
7245
Mozzarella, park skim
100g
4644
1/2 Turkey breast – no skin
306g
4562
1/2 Chicken – no skin
329g
3458
Clams mixed species
20 small (190g)
3036
Tuna, canned in oil
1 can (171g)
2391
Lean round beef, 0% fat
100g
2199
Snapped, cooked
1 fillet (170g)
2145
Chicken breast, no skin, roasted
1 cup ((140g)
2133
Halibut, cooked
1/2 fillet (159g)
2037
Canned tuna – in water
1 can (165g)
2020
Atlantic cod, cooked
1 fillet (180g)
1973
King mackerel, cooked
1/2 fillet (154g)
1922
Alaskan king crab
1 leg (172g)
1897
:Lean veal leg, cooked
100g
1886
Beef sirloin, 0% fat, cooked
100g
1844
Beef round eye, 0% fat, cooked
100g
1222
Lobster, cooked
1 cup (145g
1794

 

Glycine recommended daily intake (RDI)

RDANot necessary for healthy adults
TOLERABLE UPPER LIMIT2-10g
TOXIC LEVELSNo information available

 

Glycine works best with

Overdosage, toxicity and cautions for glycine

No clear toxicity has emerged from glycine studies, although having too much glycine in the body can cause fatigue.

Caution

People with kidney or liver disease should not consume high intakes of amino acids without consulting a health care professional.

References

  • Osiecki H, Meeke F, Smith J, The Encyclopaedia of Clinical Nutrition – Volume 1: The Nervous System, BioConceps Publishing QLD 2004
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